Jordan Roberts scored the only goal as Stevenage edged past managerless Cambridge to move back into the play-off places in Sky Bet League One.
Roberts put the hosts in front 10 minutes before the break, firing past U’s goalkeeper Jack Stevens from the edge of the box.
But Stevenage’s opener could have come earlier had it not been for Stevens saving Cambridge on two occasions.
The first stop came after Jamie Reid raced away before Kane Hemmings’ header forced Stevens to parry a second chance.
Boro finally took the lead when Roberts collected the ball and struck on the swivel for his fifth league goal of the season in the 35th minute.
Cambridge, who saw manager Neil Harris depart for Millwall last week, managed to get a foothold in the second half and Jack Lankester hit a volley just over the crossbar.
But Stevenage held on for a vital boost to their play-off hopes, reclaiming a place in the top six after a second successive 1-0 home win.
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