A warning has been issued by the HSE in relation to a "high strength" of MDMA that is circulating around Ireland since the summer.
It's been described as "very dangerous" and is causing serious health risks.
Professor Eamon Keenan, National Clinical Lead on addiction services, told RTÉ that during the summer the MDMA in question was identified and is still available.
It is three times the average dose so people are being warned that one pill does not equal one dose.
"This higher strength MDMA circulating has got significant health risks," Professor Keenan said.
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He added that although he advises people not to take drugs, they need to look out for themselves if they are going to.
If anybody sees somebody suffering from adverse consequences, they are advised to seek help immediately.
People are also being reminded that the HSE is there to support people if they do get into difficulty while taking drugs.
Professor Keenan highlighted that if help is not sought when a person starts to feel unwell, they could "deteriorate rapidly."
Symptoms of a potential overdose or adverse side effect includes, high temperatures, seizures, muscle twitches, and heart complications or a heart attack.
Due to the number of parties and gatherings that will be taking place this festive season, Professor Keenan said that the health and emergency services will see an upsurge in the number of people seeking help.
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